Jul 17, 2017
Jul 19, 2017
Employer Type
Direct Employer
Employment Type
Full Time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

The Bioassay Group in the Therapeutic Proteins Department seeks a highly motivated Research Scientist with expertise in immune assay development to support screening and lead candidate selection. The ideal candidate should have a strong immunology background and thorough understanding of immune cell development and response to immune activating stimuli. The successful candidate should possess a PhD with 2 years post doc experience. The candidate will have experience in designing, analyzing, and troubleshooting bioassays, including but not limited to, engineered cell-based reporter assays, and primary cell activation assays. Specific experience should include the development of functional primary and engineered cellular assays that quantitatively measure changes in cellular signaling activity, cytokine production, and cell proliferation/viability in response to small molecules and/or antibodies. Additionally, the candidate must be proficient in immunofluorescence staining procedures and flow cytometry. The ability to work collaboratively and communicate well both within the group and across group settings in a fast-paced team environment is essential.

Job Duties:
1) Isolate/process immune cells from human blood samples
2) Develop human primary cell-based functional assays
3) Develop cell-based functional assays using engineered-immortalized cells
4) Mammalian cell culture of adherent and non-adherent cell lines
5) Operate a variety of instruments including but not limited to HyperCyte, Accuri C6
cytometer, Cytoflex, ImageXpress micro XL, Victor, Hamilton, Envision Multilabel plate reader, Cell Harvester
6) Set up and run bioassays for screening and potency measurements
7) Provide Weekly presentations/verbal updates
8) Keep abreast of current/relevant literature in order to further develop scientific expertise and expand scientific/technical knowledge and skill sets
9) Train, direct and oversee the experimentation of research assistants
Job Requirements:

The successful candidate will have a PhD with 2+ years post doc experience
1) Extensive knowledge and background in immunology
2) Expertise in handling/processing human blood samples
3) Proficient in immunofluorescence staining procedures and flow cytometry
4) Experience in primary cell activation/proliferation assays
5) Strong aseptic cell culture skills
6) Stable cell line engineering skills
7) Cell-based potency assays

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regenerons unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.