Research Associate II-III

Recruiter
Regeneron
Location
Tarrytown
Salary
Competitive
Posted
Jul 17, 2017
Closes
Jul 19, 2017
Role
Research
Industry
Pharmaceuticals
Employer Type
Direct Employer
Employment Type
Permanent
Hours
Full Time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:
The Late Stage Bioassay Development Research Associate will perform in vitro characterization of preclinical and clinical drug candidates in Regenerons pipeline. Responsibilities will include bioassay sample testing to support preclinical development, and bioassay development and optimization. The individual will also execute experiments to characterize preclinical antibodies for cytokine release and effector function in primary cell assays to support regulatory filings.

Responsibilities:
-Mammalian cell culture of adherent and non-adherent cell lines
-Set up and run cell-based assays including dose response curves with appropriate cells
-Stable cell line generation via plasmid based and viral-based methodologies
-Isolate PBMC and NK cells and use for ex vivo analysis of effector function
-Screen cell lines for target expression by flow cytometry
- Be able to plan experiments so all necessary reagents are available and
understand the procedures involved and include appropriate controls
-Analyze data (Prism) and track data generated over time to determine assay stability
- Have written detailed protocols so experiments can be performed by anyone in the dept.
- Record data in notebook in an accurate and timely manner with appropriate
purpose, protocols and conclusions
- Communicate with both supervisor and other lab members in an effective
manner
- Present data to the departmental group clearly and accurately

Requirements:
Bachelors Degree with 2-4 years of experience
-Cell Culture (adherent and non-adherent cells)
-Luciferase Reporter Assays
-Cell Proliferation Assays
-Primary cell assays (cytokine release, proliferation, ADCC, CDC)
-Flow Cytometry
-Automated liquid handler experience (Hamilton preferred)
-Excellent Communication Skills
-Team Player
-Ability to manage multiple projects simultaneously

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regenerons unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.